Biocatalysis is a practical and environmentally friendly alternative to traditional metallo- and organocatalysis in chemical synthesis. However, in the majority of industries, the potential of biocatalysis for the sustainable manufacture of asset molecules is far from being fully realized. Despite the progress that has been made for certain enzyme classes such as ketoreductases, transaminases and the widely-used hydrolases, many of the biocatalytic reactions that have been identified in academic laboratories are not applied on an industrial scale.
Recent key advances in DNA sequencing, gene synthesis and data analysis are now enabling scientists to tailor biocatalyst according to the needs of the processes and to reorganize enzymes into new biosynthetic pathways. This progress fuels the so-called “third wave of biocatalysis” and promises to unlock hitherto inaccessible enzyme activities for industrial biocatalysis and engineer microbial and fungal strains for the production of novel asset molecules.
The mission of the platform “Biocatalysis and Biosynthesis” (founded in Dec 2015) is to promote biocatalysis and biosynthesis as a complementary method to classic synthesis and to help bridge the gap between academic laboratories and the production plant. By bundling the relevant research competences in Switzerland, the platform strives to develop a comprehensive biocatalytic toolbox consisting of enzyme libraries and methods which will facilitate the development of biocatalytic and biosynthetic processes for the chemical and pharmaceutical industry.
Industrial Biocatalysis - 10th Wädenswil Day of Life Science
Thu, 07.06.2018 - 08:30 to 17:00, ZHAW Wädenswil, Switzerland
The 2nd CCBIO Symposium will feature cutting edge topics in the field of biocatalysis, from enzyme discovery, optimization and computational design, to bioprocess engineering strategies and successful biocatalytic examples from industry. The meeting will again provide a platform for scientific knowledge transfer and dialog for participants from industry and academia in this expanding field and give an update about the current activities of the Competence Center for Biocatalysis (CCBIO).
For detailed information about agenda and talks please check: www.zhaw.ch/ccbio and 10th Wädenswil Day of Life Sciences.
3. Platform members
The platform is led by Dr. Rebecca Buller and currently has the following members.
ZHAW, Life Science and Facility Management
Fachstelle Umweltbiotechnologie, Prof. Dr. Urs Baier
Fachstelle Mess- und Sensortechnik, Prof. Dr. Caspar Demuth
Fachstelle Umweltgenomik und Systembiologie, Dr. Brion Duffy
Fachstelle Industrielle Chemie, Prof. Dr. Achim Ecker
Fachstelle Bioverfahrenstechnik und Zellkulturtechnik , Prof. Dr. Regine Eibl-Schindler und Prof. Dr. Dieter Eibl
Fachgruppe Grüne Chemie, PD Dr. Christian Frech
Fachstelle Bioprozesstechnologie, Prof. Dr. Karin Kovar und Dr. Lukas Neutsch
Fachstelle Organische Chemie, Prof. Dr. Rainer Riedl
Fachgruppe Chemical Engineering, Dr. Peter Riedlberger
Fachstelle Micro- und Molekularbiologie, Prof. Dr. Martin Sievers
Fachstelle Biochemie, Prof. Dr. Christiane Zaborosch
Laboratory of Organic Chemistry, Prof. Dr. Donald Hilvert
Department Biotechnologie und Enzyme Engineering, Prof. Dr. Uwe Bornscheuer
Lehrstuhl für Bioprozesstechnik, Prof. Dr. Ruth Freitag
ChemTech, Prof. Dr. Roger Marti
Dr. Hans-Peter Meyer
Firmenich SA, Genf
Dr. Andreas Taglieber
Givaudan SA, Kemptthal
Dr. Thomas Münch