1. History and mission
The discovery of antibiotics during the course of the 20th century was a milestone in the history of medicine. Today, a remarkable number of antibiotics still stem from the golden era of antibiotics development, which lasted roughly from 1945-1970. Unfortunately, antibiotics became victims of their own success; due to many treatment options and low prices, companies ceased to develop novel antibiotics, because other medical fields offered more attractive markets. In parallel, the existing antibiotics were misused as food additives in the animal industry and were prescribed to humans without being necessary. As a consequence, antimicrobial resistance could spread worldwide, resulting in multiresistant pathogens which can no longer be treated with the current arsenal of antibiotics. In particular Gram-negative pathogens such as Escherichia coli and Klebsiella pneumonia and Pseudomonas aeruginosa have emerged as dangerous multiresistant strains in western hospitals including Switzerland.
In 2015, biotechnet and the NTN SwissBiotech founded a novel platform dedicated to antibiotics. The mission of the Antibiotics platform is to bundle the existing expertise of antibiotic research in Switzerland with a focus on the discovery and development of novel antibiotics to treat multidrug resistant bacteria. Networking activities facilitated through the Antibiotics platform will lead to novel research co-operations between industry and academia. Together, we strive to innovate antibiotic development.
2. Platform members
The platform is lead by Prof. Dr. Markus Seeger and has currently the following members
Actelion, Dr. Daniel Ritz
Basilea Pharmaceutica Ltd., Dr. Jürg Dreier
BioVersys, Dr. Michel Pieren
Laves-Arzneimittel GmbH, Dr. Dieter Grimmecke
Polyphor, Dr. Daniel Obrecht
rqmicro, Dr. Hans-Anton Keserue
EPF Lausanne, Global Health Institute, Prof. Dr. Stewart Cole
ETH Zurich, Institute of Microbiology, Prof. Dr. Jörn Piel
ETH Zurich, Institute of Pharmaceutical Sciences, Prof. Dr. Karl-Heinz Altmann
FHNW School of Life Sciences, Institute for Chemistry and Bioanalytics, Prof. Dr. Daniel Gygax and Prof. Dr. Eric Kübler
HES-SO Valais-Wallis, Institute of Life Technologies, Prof. Dr. Origène Nyanguile
ZHAW Life Sciences und Facility Management, Center of Organic and Medicinal Chemistry, Prof. Dr. Rainer Riedl
University of Basel, Department of Chemistry, Dr. Marc Creus
University of Basel, Biozentrum, Prof. Dr. Sebastian Hiller
University of Berne, Institute for Veterinary Bacteriology, Prof. Dr. Vincent Perreten
University of Palermo, Prof. Dr. Anna Maria Puglia
University of Zurich, Department of Chemistry, Prof. Dr. John Robinson
University of Zurich, Institute of Medical Microbiology, Prof. Dr. Markus Seeger
2.3 How to become partner
The partnership fee is CHF 500.- per year. Please contact Prof. Dr. Markus Seeger for details.
3. Events and News
3.2 Upcoming events
3.3 Past events
20. June 2016
Platform meeting at Polyphor, Allschwil.
The event will start at 11.00 and end at around 16.00
18. November 2015
Olten Meeting 2015. Antibiotics and Bioprinting.
The program can be seen here:
08. September 2015
Founding meeting of the Antibiotics Platform in Berne.
4. CTI-Projects of platform members
Development of early lead-like molecules targeting a bacterial transcriptional regulator to treat infections caused by the Gram-negative pathogen Acinetobacter baumannii.
BioVersys in collaboration with Dr. Richard Kammerer, PSI
5. Read more
Article about Antibiotics Platform in Chimia
Artikel über Antibiotika Plattform in ChemiePlus
Artikel über Olten Meeting 2015 in ChemiePlus